At last, a “gold standard” study showing Telomere Lengthening in Humans!
Full text of the study is here.
Dr Ed. Park summarizes the results:
At last, we have a well-designed study showing TA-65 lengthens telomeres in human subjects.
Salvador et al (Rejuvenation Research.2016 Mar 30]
This was a double-blinded (patients and researchers not aware what substance was taken), placebo-controlled (half were given ‘inactive’ substances), randomized controlled trial (assignment to treatment at two doses versus non-treatment was done randomly therefore minimizing the risk of unknown confounding variables). The study was small but that is only a problem if you don’t find something. In this case, findings did reach statistical significance for the low dose TA-65 and control groups.
The study was conducted on 117 relatively healthy Barcelonian cytomegalovirus-positive subjects aged 53–87 years old.
23 subjects received one TA-65 capsule (250 U) and three placebo capsules;
22 subjects received four TA-65 capsules, each consisting of 250 U of TA-65 (i.e., 1000 U/4 capsules).
Fifty-two subjects received four placebo capsules.
Here is a table highlighting the statistically-significantly findings:
As we can see, there was a decrease of 290 base pairs among the placebo group and an increase in 530 base pairs. Compared with the placebo group and assuming 100 base pair erosion per year (actually can vary a lot but 50-200 is typical), we can say that the low-dose TA-65 group GAINED SEVEN YEARS of viable telomere length.
My comments: This is such great news! At last, we have more than just in vitro and anecdotal evidence that we can lengthen our telomeres!
The study used TA-65 and the high quality Life Length telomere length test. I’ve begun the process of contacting Isagenix about having them duplicate the test using their “Product B”, the only other commercially available natural product shown to activate telomerase in Sierra Sciences in vitro telomerase activation assay.
I judge that this new level of evidence for the previously thought to be impossible prospect of age reversal will be a “game changer” when it comes to helping people to consider the possibility of getting younger.